2000 UW-Platteville Football Schedule
| Date | Opponent | Result | Site |
| 9/9 | at Mount Senario | W, 26-19 | Ladysmith, WI |
| 9/16 | Augustana | L, 3-32 | Pioneer Stadium |
| 9/23 | UW-Whitewater* | L, 6-26 | Pioneer Stadium |
| 9/30 | UW-Eau Claire* (Homecoming) | L, 6-30 | Pioneer Stadium |
| 10/7 | at UW-La Crosse* | L, 0-30 | La Crosse, WI |
| 10/14 | at UW-Oshkosh* | W, 28-24 | Oshkosh, WI |
| 10/21 | UW-Stout* | L, 35-43 | Pioneer Stadium |
| 10/28 | at UW-Stevens Point* | L, 7-14 | Stevens Point, WI |
| 11/4 | UW-River Falls* | L, 7-52 | Pioneer Stadium |
| 11/11-12 | vs. Southwest State | L, 30-52 | HHH Metrodome, Minneapolis, MN |
*Wisconsin Intercollegiate Athletic Conference Games